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If you buy Hydrocodone vicodin, you need to know that is an opioid-type medication that comes from codeine and is indicated for the treatment of pain of moderate to severe intensity being administered orally. In turn it also has the benefit of reducing and eliminating cough thanks to the fact that hydrocodone stimulates a central action in the brain. From a more strict point of view, hydrocodone is usually used when a person requires an analgesic that is effective in order to alleviate a pain of a strong character and that manifests itself permanently for a long time. In addition to these aspects, it is also recommended for those patients who cannot take other types of medications. Vicodin exerts its action on the central nervous system (CNS) and is considered to be possible thanks to the existence of opiate receptors in the CNS. In turn the opinion of doctors and specialists coincide to estimate that this medicine is the analgesic of oral administration that offers greater potency and effectiveness and can be bought without the need of having medical prescription. Vicodin is approved and regulated by the FDA.

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The analgesic effect of hydrocodone is maintained for 4 or 5 hours and begins after approximately 20 minutes of taking it. Doctors have determined that the dose of this medication can be modified according to the intensity of the pain suffered, as well as its assimilation by the patient’s body. Given this consideration, numerous studies and clinical guidelines recommend that the usual dose for adults is 10 mg for oral administration and people using hydrocodone should establish an interval ranging from 4 to 6 hours. It is also important to mention that a maximum dose has not been defined for those people who end up being resistant to vicodin. As for children, it is stipulated that the dose is 0.15 mg / kg and a pill should be taken every six hours.

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The efficacy of this pain-relieving opioid analgesic has been evidenced by evidence from numerous studies. An investigation published in The Annals of Emergency Medicine Journal evaluated the action of hydrocodone for the management of acute musculoskeletal pain compared to codeine. Sixty-two patients between the ages of 18 and 70 participated in the study, divided into two groups. One of the groups took 5 mg of hydrocodone combined with acetaminophen while the other group was given 30 mg of codeine also in conjunction with acetaminophen. The results observed and analyzed by the researchers showed that the intensity of the pain was similar for both groups although hydrocodone managed to be slightly more effective. As for the adverse effects, no great differences were found between vicodin and codeine. However in the comparison the former proved to produce fewer side effects. First, 18 patients who were given codeine had adverse effects. Conversely, only eight patients reported side effects when taking hydrocodone. Second, fewer cases of nausea and vomiting were reported in those individuals who were treated with vicodin. Finally, central nervous system adverse events occurred in 6 patients who had taken hydrocodone while the number increased to 16 patients compared to the group receiving codeine. Together these data led the researchers to conclude that when evaluating effectiveness and adverse effects, hydrocodone is superior achieving adequate analgesia. Therefore it was affirmed that it is a therapeutic option that is more effective and a better cost-benefit to the detriment of hydrocodone.

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Other evidence supporting the use of vicodin may be found in a study published in Expert Opinion in Pharmacology. This was an investigation that evaluated the efficacy and safety of hydrocodone for the management of back pain. Specifically, we considered those cases in which a pain ranging from mild to severe pain is experienced. Individuals selected to be part of the study took a dose of 20 to 120 mg hydrocodone tablets once daily. These individuals had both moderate and severe chronic pain from low back pain. The researchers found that vicodin was able to alleviate or decrease pain when compared to placebo. In addition, this analgesic efficacy was maintained in the course of 12 weeks, a period that the researchers defined for an evaluation. Complementarily hydrocodone was also found to be more beneficial than placebo since it was very well tolerated by all subjects studied. Thus, it was concluded that the drug should be evaluated as an effective and quality therapeutic strategy to face back pain as it also did not generate greater adverse effects constituting itself as a drug that has a good safety profile.

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Finally, it is also possible to refer to other research that was released in Postgraduate Medicine. In that study we analyzed how effective and safe is hydrocodone to treat chronic pain. For this, it was evaluated whether it was more convenient to take only vicodin compared to the combination of this drug and acetaminophen. It was found that hydrocodone had better results to calm the pain and in turn did not entail serious adverse effects than usual. Therefore, the use of this drug is guaranteed as one of the best options to decrease the intensity of the pain and to ensure that its effects remain the adequate time that the patient requires.

Finally, it should be noted that hydrocodone can be taken if it is being treated with other drugs except antihistamines, antipsychotics, anxiolytics or other depressants of the central nervous system. In turn, several experts have considered that taking hydrocodone simultaneously with other analgesics can achieve an increase in drug efficacy without resulting in major side effects.

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